Brooks EC, Han SJY, Bonatto Paese CL, Lewis AA, Aarnio-Peterson M, Brugmann SA. The ciliary protein C2cd3 is required for mandibular musculoskeletal tissue patterning. Differentiation. 2024 May 23;138:100782. doi: 10.1016/j.diff.2024.100782. PMID: 38810379
Wilderman A, D’haene E, Baetens M, Yankee TN, Winchester EW, Glidden N, Roets E, Van Dorpe J, Janssens S, Miller DE, Galey M, Brown KM, Stottmann RW, Vergult S, Weaver KN, Brugmann SA, Cox TC, Cotney J. A distant global control region is essential for normal expression of anterior HOXA genes during mouse and human craniofacial development. Nat Commun. 2024 Jan 2;15(1):136. doi: 10.1038/s41467-023-44506-2. PubMed PMID: 38167838; PubMed Central PMCID: PMC10762089.
Elliott KH, Balchand SK, Bonatto Paese CL, Chang CF, Yang Y, Brown KM, Rasicci DT, He H, Thorner K, Chaturvedi P, Murray SA, Chen J, Porollo A, Peterson KA, Brugmann SA. Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation. Development. 2023 Apr 15;150(8). doi: 10.1242/dev.201237. Epub 2023 Apr 27. PubMed PMID: 36971348. select
Bonatto Paese CL, Chang CF, Kristeková D, Brugmann SA. Pharmacological intervention of the FGF-PTH axis as a potential therapeutic for craniofacial ciliopathies. Dis Model Mech. 2022 Aug 1;15(8). doi: 10.1242/dmm.049611. Epub 2022 Aug 16. PubMed PMID: 35818799; PubMed Central PMCID: PMC9403750. select
Brugmann SA, Merrill AE, Saint-Jeannet JP, Stottmann RW, Clouthier DE. The Society for Craniofacial Genetics and Developmental Biology 44th Annual Meeting. Am J Med Genet A. 2022 Jul;188(7):2258-2266. doi: 10.1002/ajmg.a.62731. Epub 2022 Mar 29. PubMed PMID: 35352468. select
Pagliaroli L, Porazzi P, Curtis AT, Scopa C, Mikkers HMM, Freund C, Daxinger L, Deliard S, Welsh SA, Offley S, Ott CA, Calabretta B, Brugmann SA, Santen GWE, Trizzino M. Inability to switch from ARID1A-BAF to ARID1B-BAF impairs exit from pluripotency and commitment towards neural crest formation in ARID1B-related neurodevelopmental disorders. Nat Commun. 2021 Nov 9;12(1):6469. doi: 10.1038/s41467-021-26810-x. PubMed PMID: 34753942; PubMed Central PMCID: PMC8578637. select
Bonatto Paese CL, Hawkins MB, Brugmann SA, Harris MP. Atavisms in the avian hindlimb and early developmental polarity of the limb. Dev Dyn. 2021 Sep;250(9):1358-1367. doi: 10.1002/dvdy.318. Epub 2021 Mar 1. PubMed PMID: 33605505; PubMed Central PMCID: PMC8373999. select
Chang CF, Brown KM, Yang Y, Brugmann SA. Centriolar Protein C2cd3 Is Required for Craniofacial Development. Front Cell Dev Biol. 2021;9:647391. doi: 10.3389/fcell.2021.647391. eCollection 2021. PubMed PMID: 34211969; PubMed Central PMCID: PMC8239364. select
Brugmann S, Clouthier DE, Saint-Jeannet JP, Taneyhill LA, Moody SA. The society for craniofacial genetics and developmental biology 43rd annual meeting. Am J Med Genet A. 2021 Jun;185(6):1932-1939. doi: 10.1002/ajmg.a.62150. Epub 2021 Mar 4. PubMed PMID: 33660912. select
Brooks EC, Bonatto Paese CL, Carroll AH, Struve JN, Nagy N, Brugmann SA. Mutation in the Ciliary Protein C2CD3 Reveals Organ-Specific Mechanisms of Hedgehog Signal Transduction in Avian Embryos. J Dev Biol. 2021 Mar 25;9(2). doi: 10.3390/jdb9020012. PubMed PMID: 33805906; PubMed Central PMCID: PMC8103285. select
Bonatto Paese CL, Brooks EC, Aarnio-Peterson M, Brugmann SA. Ciliopathic micrognathia is caused by aberrant skeletal differentiation and remodeling. Development. 2021 Feb 15;148(4). doi: 10.1242/dev.194175. PubMed PMID: 33589509; PubMed Central PMCID: PMC7903998. select
Elliott KH, Chen X, Salomone J, Chaturvedi P, Schultz PA, Balchand SK, Servetas JD, Zuniga A, Zeller R, Gebelein B, Weirauch MT, Peterson KA, Brugmann SA. Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks. Elife. 2020 Oct 2;9. doi: 10.7554/eLife.56450. PubMed PMID: 33006313; PubMed Central PMCID: PMC7556880. select
Elliott KH, Brugmann SA. Sending mixed signals: Cilia-dependent signaling during development and disease. Dev Biol. 2019 Mar 1;447(1):28-41. doi: 10.1016/j.ydbio.2018.03.007. Epub 2018 Mar 13. Review. PubMed PMID: 29548942; PubMed Central PMCID: PMC6136992. select
Elliott KH, Millington G, Brugmann SA. A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development. Dev Dyn. 2018 Jun;247(6):818-831. doi: 10.1002/dvdy.24627. Epub 2018 Apr 10. PubMed PMID: 29532549; PubMed Central PMCID: PMC5980737. select
Schock EN, Brugmann SA. Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division. Dev Biol. 2017 Nov 15;431(2):168-178. doi: 10.1016/j.ydbio.2017.09.026. Epub 2017 Sep 21. PubMed PMID: 28941984; PubMed Central PMCID: PMC5658255. select
Schock EN, Brugmann SA. Discovery, Diagnosis, and Etiology of Craniofacial Ciliopathies. Cold Spring Harb Perspect Biol. 2017 Sep 1;9(9). doi: 10.1101/cshperspect.a028258. Review. PubMed PMID: 28213462; PubMed Central PMCID: PMC5585846. select
Millington G, Elliott KH, Chang YT, Chang CF, Dlugosz A, Brugmann SA. Cilia-dependent GLI processing in neural crest cells is required for tongue development. Dev Biol. 2017 Apr 15;424(2):124-137. doi: 10.1016/j.ydbio.2017.02.021. Epub 2017 Mar 9. PubMed PMID: 28286175; PubMed Central PMCID: PMC5420199. select
Workman MJ, Mahe MM, Trisno S, Poling HM, Watson CL, Sundaram N, Chang CF, Schiesser J, Aubert P, Stanley EG, Elefanty AG, Miyaoka Y, Mandegar MA, Conklin BR, Neunlist M, Brugmann SA, Helmrath MA, Wells JM. Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system. Nat Med. 2017 Jan;23(1):49-59. doi: 10.1038/nm.4233. Epub 2016 Nov 21. PubMed PMID: 27869805; PubMed Central PMCID: PMC5562951. select
Chang CF, Chang YT, Millington G, Brugmann SA. Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline. PLoS Genet. 2016 Nov;12(11):e1006351. doi: 10.1371/journal.pgen.1006351. eCollection 2016 Nov. PubMed PMID: 27802276; PubMed Central PMCID: PMC5089743. select
Chang YT, Chaturvedi P, Schock EN, Brugmann SA. Understanding Mechanisms of GLI-Mediated Transcription during Craniofacial Development and Disease Using the Ciliopathic Mutant, talpid2. Front Physiol. 2016;7:468. doi: 10.3389/fphys.2016.00468. eCollection 2016. PubMed PMID: 27799912; PubMed Central PMCID: PMC5065992. select
Schock EN, Chang CF, Youngworth IA, Davey MG, Delany ME, Brugmann SA. Utilizing the chicken as an animal model for human craniofacial ciliopathies. Dev Biol. 2016 Jul 15;415(2):326-337. doi: 10.1016/j.ydbio.2015.10.024. Epub 2015 Oct 24. Review. PubMed PMID: 26597494; PubMed Central PMCID: PMC4842343. select
Romick-Rosendale LE, Hoskins EE, Privette Vinnedge LM, Foglesong GD, Brusadelli MG, Potter SS, Komurov K, Brugmann SA, Lambert PF, Kimple RJ, Virts EL, Hanenberg H, Gillison ML, Wells SI. Defects in the Fanconi Anemia Pathway in Head and Neck Cancer Cells Stimulate Tumor Cell Invasion through DNA-PK and Rac1 Signaling. Clin Cancer Res. 2016 Apr 15;22(8):2062-73. doi: 10.1158/1078-0432.CCR-15-2209. Epub 2015 Nov 24. PubMed PMID: 26603260; PubMed Central PMCID: PMC4834270. select
Schock EN, Chang CF, Struve JN, Chang YT, Chang J, Delany ME, Brugmann SA. Using the avian mutant talpid2 as a disease model for understanding the oral-facial phenotypes of oral-facial-digital syndrome. Dis Model Mech. 2015 Aug 1;8(8):855-66. doi: 10.1242/dmm.020222. Epub 2015 Jun 4. PubMed PMID: 26044959; PubMed Central PMCID: PMC4527291. select
Saal HM, Prows CA, Guerreiro I, Donlin M, Knudson L, Sund KL, Chang CF, Brugmann SA, Stottmann RW. A mutation in FRIZZLED2 impairs Wnt signaling and causes autosomal dominant omodysplasia. Hum Mol Genet. 2015 Jun 15;24(12):3399-409. doi: 10.1093/hmg/ddv088. Epub 2015 Mar 10. PubMed PMID: 25759469; PubMed Central PMCID: PMC4834928. select
Chang CF, Schock EN, Attia AC, Stottmann RW, Brugmann SA. The ciliary baton: orchestrating neural crest cell development. Curr Top Dev Biol. 2015;111:97-134. doi: 10.1016/bs.ctdb.2014.11.004. Epub 2015 Jan 22. Review. PubMed PMID: 25662259; PubMed Central PMCID: PMC9077745. select
Chang CF, Schock EN, O’Hare EA, Dodgson J, Cheng HH, Muir WM, Edelmann RE, Delany ME, Brugmann SA. The cellular and molecular etiology of the craniofacial defects in the avian ciliopathic mutant talpid2. Development. 2014 Aug;141(15):3003-12. doi: 10.1242/dev.105924. PubMed PMID: 25053433; PubMed Central PMCID: PMC4197679. select
Brugmann SA, Wells JM. Building additional complexity to in vitro-derived intestinal tissues. Stem Cell Res Ther. 2013;4 Suppl 1:S1. doi: 10.1186/scrt362. Epub 2013 Dec 20. Review. PubMed PMID: 24565179; PubMed Central PMCID: PMC4029141. select
Liu H, Lan Y, Xu J, Chang CF, Brugmann SA, Jiang R. Odd-skipped related-1 controls neural crest chondrogenesis during tongue development. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18555-60. doi: 10.1073/pnas.1306495110. Epub 2013 Oct 28. PubMed PMID: 24167250; PubMed Central PMCID: PMC3831959. select
Rada-Iglesias A, Bajpai R, Prescott S, Brugmann SA, Swigut T, Wysocka J. Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest. Cell Stem Cell. 2012 Nov 2;11(5):633-48. doi: 10.1016/j.stem.2012.07.006. Epub 2012 Sep 13. PubMed PMID: 22981823; PubMed Central PMCID: PMC3751405. select
Powder KE, Ku YC, Brugmann SA, Veile RA, Renaud NA, Helms JA, Lovett M. A cross-species analysis of microRNAs in the developing avian face. PLoS One. 2012;7(4):e35111. doi: 10.1371/journal.pone.0035111. Epub 2012 Apr 16. PubMed PMID: 22523571; PubMed Central PMCID: PMC3327661. select
Lenton K, James AW, Manu A, Brugmann SA, Birker D, Nelson ER, Leucht P, Helms JA, Longaker MT. Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling. Genesis. 2011 Oct;49(10):784-96. doi: 10.1002/dvg.20768. Epub 2011 Aug 24. PubMed PMID: 21557453. select
Zaghloul NA, Brugmann SA. The emerging face of primary cilia. Genesis. 2011 Apr;49(4):231-46. doi: 10.1002/dvg.20728. Epub 2011 Apr 1. Review. PubMed PMID: 21305689; PubMed Central PMCID: PMC3118297. select
Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT. Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-1190. doi: 10.1097/PRS.0b013e3182043a07. PubMed PMID: 21364421; PubMed Central PMCID: PMC3078688. select
Rada-Iglesias A, Bajpai R, Swigut T, Brugmann SA, Flynn RA, Wysocka J. A unique chromatin signature uncovers early developmental enhancers in humans. Nature. 2011 Feb 10;470(7333):279-83. doi: 10.1038/nature09692. Epub 2010 Dec 15. PubMed PMID: 21160473; PubMed Central PMCID: PMC4445674. select
Brugmann SA, Cordero DR, Helms JA. Craniofacial ciliopathies: A new classification for craniofacial disorders. Am J Med Genet A. 2010 Dec;152A(12):2995-3006. doi: 10.1002/ajmg.a.33727. Review. PubMed PMID: 21108387; PubMed Central PMCID: PMC3121325. select
Brugmann SA, Allen NC, James AW, Mekonnen Z, Madan E, Helms JA. A primary cilia-dependent etiology for midline facial disorders. Hum Mol Genet. 2010 Apr 15;19(8):1577-92. doi: 10.1093/hmg/ddq030. Epub 2010 Jan 27. PubMed PMID: 20106874; PubMed Central PMCID: PMC2846163. select
Brugmann SA, Powder KE, Young NM, Goodnough LH, Hahn SM, James AW, Helms JA, Lovett M. Comparative gene expression analysis of avian embryonic facial structures reveals new candidates for human craniofacial disorders. Hum Mol Genet. 2010 Mar 1;19(5):920-30. doi: 10.1093/hmg/ddp559. Epub 2009 Dec 16. PubMed PMID: 20015954; PubMed Central PMCID: PMC2816616. select
James AW, Theologis AA, Brugmann SA, Xu Y, Carre AL, Leucht P, Hamilton K, Korach KS, Longaker MT. Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion. PLoS One. 2009 Sep 22;4(9):e7120. doi: 10.1371/journal.pone.0007120. PubMed PMID: 19771170; PubMed Central PMCID: PMC2743190. select
ten Berge D, Brugmann SA, Helms JA, Nusse R. Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development. Development. 2008 Oct;135(19):3247-57. doi: 10.1242/dev.023176. PubMed PMID: 18776145; PubMed Central PMCID: PMC2756806. select
Schlosser G, Awtry T, Brugmann SA, Jensen ED, Neilson K, Ruan G, Stammler A, Voelker D, Yan B, Zhang C, Klymkowsky MW, Moody SA. Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion. Dev Biol. 2008 Aug 1;320(1):199-214. doi: 10.1016/j.ydbio.2008.05.523. Epub 2008 May 20. PubMed PMID: 18571637; PubMed Central PMCID: PMC2671077. select
Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY. A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes Dev. 2008 Feb 1;22(3):303-7. doi: 10.1101/gad.1610508. PubMed PMID: 18245445; PubMed Central PMCID: PMC2216690. select
Brugmann SA, Goodnough LH, Gregorieff A, Leucht P, ten Berge D, Fuerer C, Clevers H, Nusse R, Helms JA. Wnt signaling mediates regional specification in the vertebrate face. Development. 2007 Sep;134(18):3283-95. doi: 10.1242/dev.005132. Epub 2007 Aug 15. PubMed PMID: 17699607; NIHMSID:NIHMS345533. select
Helms JA, Brugmann SA. The origins of species-specific facial morphology: the proof is in the pigeon. Integr Comp Biol. 2007 Sep;47(3):338-42. doi: 10.1093/icb/icm051. Epub 2007 Jun 22. PubMed PMID: 21672843. select
Goodnough LH, Brugmann SA, Hu D, Helms JA. Stage-dependent craniofacial defects resulting from Sprouty2 overexpression. Dev Dyn. 2007 Jul;236(7):1918-28. doi: 10.1002/dvdy.21195. PubMed PMID: 17576140. select
Rinn JL, Kertesz M, Wang JK, Squazzo SL, Xu X, Brugmann SA, Goodnough LH, Helms JA, Farnham PJ, Segal E, Chang HY. Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell. 2007 Jun 29;129(7):1311-23. doi: 10.1016/j.cell.2007.05.022. PubMed PMID: 17604720; PubMed Central PMCID: PMC2084369. select
Brugmann SA, Kim J, Helms JA. Looking different: understanding diversity in facial form. Am J Med Genet A. 2006 Dec 1;140(23):2521-9. doi: 10.1002/ajmg.a.31361. PubMed PMID: 16838331. select
Brugmann SA, Tapadia MD, Helms JA. The molecular origins of species-specific facial pattern. Curr Top Dev Biol. 2006;73:1-42. doi: 10.1016/S0070-2153(05)73001-5. Review. PubMed PMID: 16782454. select
Brugmann SA, Moody SA. Induction and specification of the vertebrate ectodermal placodes: precursors of the cranial sensory organs. Biol Cell. 2005 May;97(5):303-19. doi: 10.1042/BC20040515. Review. PubMed PMID: 15836430. select
Brugmann SA, Pandur PD, Kenyon KL, Pignoni F, Moody SA. Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor. Development. 2004 Dec;131(23):5871-81. doi: 10.1242/dev.01516. Epub 2004 Nov 3. PubMed PMID: 15525662; NIHMSID:NIHMS381438. select
The Society for Craniofacial Genetics and Developmental Biology 44th Annual Meeting. American journal of medical genetics. Part A. . NIHMSID: NIHMS1800099. select
The society for craniofacial genetics and developmental biology 43rd annual meeting. American journal of medical genetics. Part A. . NIHMSID: NIHMS1800100.